![]() The evidence from animal models and human studies is considered. Methodological and technological advances have made it possible to undertake the molecular dissection of the genetic component of complex, multifactorial traits, such as those of interest to exercise biology, in terms of tissue expression profile, genes, and allelic variants. There is evidence from genetic epidemiology research that DNA sequence differences contribute to human variation in physical activity level, cardiorespiratory fitness in the untrained state, cardiovascular and metabolic response to acute exercise, and responsiveness to regular exercise. ![]() ![]() This chapter is devoted to the role of genetic variation and gene-exercise interactions in the biology of adaptation to exercise. ![]()
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March 2023
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